abstract：BACKGROUND:The objective of this study was to improve the feasibility of applying topic 5-aminolevulinic acid (ALA) in photodiagnosis (PD) and treatment of condyloma caused by human papillomavirus (HPV) using two homemade handheld devices and to discuss the photodynamic therapy (PDT) as a suitable alternative for each ...

journal_title：Photodiagnosis and photodynamic therapy

authors： Inada NM,Costa MM,Guimarães OC,Ribeiro Eda S,Kurachi C,Quintana SM,Lombardi W,Bagnato VS

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Tumor markers are commonly used for cancer screening and as indicators of therapeutic effects. Certain types of tumor have been known to produce a variety of porphyrins after 5-aminolevulinic acid (ALA) administration. In this study, porphyrins in tumor-bearing mouse urine were analyzed after oral administra...

journal_title：Photodiagnosis and photodynamic therapy

authors： Ishizuka M,Hagiya Y,Mizokami Y,Honda K,Tabata K,Kamachi T,Takahashi K,Abe F,Tanaka T,Nakajima M,Ogura S,Okura I

更新日期：2011-12-01 00:00:00

abstract：:Extramedullary plasmacytomas (EMP) are rare plasma cell neoplasms that are mostly located in the mucosal surfaces of the upper aerodigestive tract. The standard treatment is radiotherapy (RT), with surgical resection reserved as salvage procedure. In this report a patient with a EMP, located in the nasopharynx and ref...

journal_title：Photodiagnosis and photodynamic therapy

authors： Karakullukcu B,De Boer JP,Van Veen R,Wegman J,Tan B

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Although discovered over a century ago it is only in the last 25 years that photodynamic therapy (PDT) has been the focus of intense research. This versatile treatment modality has been shown to be effective in treating a wide variety of malignancies, and with the increasing incidence of non-melanoma skin ca...

journal_title：Photodiagnosis and photodynamic therapy

authors： Lesar A,Ferguson J,Moseley H

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The objective of this paper was to verify if the oral administration of δ-aminolevulinic acid (ALA) in animals with prostate tumor can increase the sensitivity of cancer diagnosis by protoporphyrin IX blood autofluorescence. In this study, the autofluorescence of blood porphyrin was analyzed using fluorescen...

journal_title：Photodiagnosis and photodynamic therapy

authors： Silva FR,Bellini MH,Nabeshima CT,Schor N,Vieira ND Jr,Courrol LC

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The photosensitizer pro-drug 5-aminolevulinic acid (5-ALA) has been administered systemically for photodynamic therapy. Although several toxicities have been reported, nephrotoxicity has never been observed. MATERIALS AND METHODS:Patients with head and neck mucosal dysplasia have been treated on a phase 1 s...

journal_title：Photodiagnosis and photodynamic therapy

authors： Quon H,Grossman CE,King RL,Putt M,Donaldson K,Kricka L,Finlay J,Zhu T,Dimofte A,Malloy K,Cengel KA,Busch TM

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The focal goal of this study is to identify optimal accumulation periods for ALA-induced PpIX in different healthy anatomical sites of human oral cavity and different types of abnormal mucosa to improve the accuracy of the clinical applications such as photodiagnosis and tissue grading. MATERIALS AND METHOD...

journal_title：Photodiagnosis and photodynamic therapy

authors： Mallia RJ,Subhash N,Sebastian P,Kumar R,Thomas SS,Mathews A,Madhavan J

更新日期：2010-09-01 00:00:00

abstract：:We present the successful use of interstitial photodynamic therapy in the treatment of lacrimal gland mantle cell lymphoma associated with cervical and axillary lymphadenopathy in a 59-year-old female. ...

journal_title：Photodiagnosis and photodynamic therapy

authors： Hamdoon Z,Jerjes W,Upile T,Osher J,Hopper C

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Epithelial non-melanoma skin cancer (NMSC) like actinic keratosis (AK), Bowen's disease (BD) and basal cell carcinoma (BCC) represent the most common malignancies in the fair skinned population. Epidemiological data reveal high incidences, especially for actinic keratoses, which are basically non-invasive sq...

journal_title：Photodiagnosis and photodynamic therapy

authors： Sidoroff A,Thaler P

更新日期：2010-03-01 00:00:00

abstract：:Port wine stain (PWS) birthmarks are congenital vascular malformations characterized by ectatic capillaries in the papillary layer of the dermis. They usually appear at birth and tend to become darker and thicker with age. Cosmetic and pathological changes can cause great depression in all ages. Laser-mediated selecti...

journal_title：Photodiagnosis and photodynamic therapy

authors： Yuan KH,Li Q,Yu WL,Huang Z

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:This paper provides the results of the non-clinical evaluation of biodistribution of the PS Photolon in inner organs and tissues of intact and tumor-bearing rats with xenograft tumors of different morphologic types. METHODS:The accumulation studies were performed in rats by means of intravital laser fluorim...

journal_title：Photodiagnosis and photodynamic therapy

authors： Shliakhtsin SV,Trukhachova TV,Isakau HA,Istomin YP

更新日期：2009-06-01 00:00:00

abstract：:We have more than 10 years experience in the Photobiology Unit, in the use of topical photodynamic therapy (PDT) for non-melanoma skin cancer and other skin diseases. During this time we have undertaken approximately 5000 treatments and this article details the practical aspects of how we treat Bowen's disease with to...

journal_title：Photodiagnosis and photodynamic therapy

authors： Attili SK,Ibbotson SH

更新日期：2009-03-01 00:00:00

abstract：:Basal cell carcinoma is one of the most common neoplasmatic diseases of the skin. Oral leukoplakia is precancerous stage. Early diagnosis of both diseases gives very good treatment results. Fluorescence spectroscopy is a new modality of diagnostics using excitation of absorbed PPIX in tumor. Spectroscopy is an objecti...

journal_title：Photodiagnosis and photodynamic therapy

authors： Sieron A,Gibinski P,Pustelny T,Kwiatek S,Opilski Z,Kawczyk-Krupka A,Woznica T,Maciak E,Kubica W,Urbanczyk M,Latos W

更新日期：2008-12-01 00:00:00

abstract：:Photodynamic effect was a chance discovery early in the 1900s, demonstrating the lethal effects of light activated chemicals on living cells. Although the application of the principles of photodynamic effect to patients' treatment and what became photodynamic therapy (PDT) was practiced in 1960s and 1970s, clinical tr...

journal_title：Photodiagnosis and photodynamic therapy

authors： Mitton D,Ackroyd R

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Autofluorescence bronchoscopy (AFB) is a highly sensitive tool for the detection of early bronchial cancers. However, its specificity remains limited due to primarily false positive results induced by hyperplasia, metaplasia and inflammation. We have investigated the potential of blue-violet backscattered li...

journal_title：Photodiagnosis and photodynamic therapy

authors： Gabrecht T,Radu A,Grosjean P,Weber B,Reichle G,Freitag L,Monnier P,van den Bergh H,Wagnières G

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The gold standard treatment of early oesophageal carcinoma is oesophagectomy but the elderly population affected are often medically unfit for this radical intervention and less invasive curative options are required. We describe our experience of porfimer sodium photodynamic therapy (PDT) as an alternative ...

journal_title：Photodiagnosis and photodynamic therapy

authors： Craig C,Gray J,Macpherson M,Hodgson H,Zammit M,Fullarton G

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Optical fibres can be placed in balloons to deliver light for intracranial photodynamic therapies. METHOD:A series of fibres, with either cleaved ends or terminating in cylindrical diffusers, housed in two different balloons, containing various solutions were investigated. The aim of the experiments perform...

journal_title：Photodiagnosis and photodynamic therapy

authors： Moseley H,Mclean C,Hockaday S,Eljamel S

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To investigate the clinical application of 5-aminolevulinic acid (ALA) assisted fluorescence cystoscopy for early detection of bladder carcinoma and completely transurethral resection. METHOD:ALA-assisted fluorescence cystoscopy was performed on 51 cases of anodynia haematuria. Fluorescence cystoscopy was perf...

journal_title：Photodiagnosis and photodynamic therapy

authors： Song X,Ye Z,Zhou S,Yang W,Zhang X,Liu J,Ma Y

更新日期：2007-03-01 00:00:00

abstract：:Head and neck (H&N) cancer patients have a high incidence of local field change as well as second primary lung tumours. We have applied the Wolf Diagnostic Autofluorescence Endoscopy (DAFE) system in a novel way, combining autofluorescence evaluation of both H&N region and bronchial. New H&N cases as well as "old" cas...

journal_title：Photodiagnosis and photodynamic therapy

authors： Fielding D,Agnew J,Wright D,Hodge R

更新日期：2006-12-01 00:00:00

abstract：:Four tetracationic porphyrins have been investigated for their ability to photo-inactivate Leishmania major promastigotes. Parallel photocytotoxicity assays against keratinocytes and macrophages show significant differences in activity between the microorganism and mammalian cells. Results suggest that it may be possi...

journal_title：Photodiagnosis and photodynamic therapy

authors： Bristow CA,Hudson R,Paget TA,Boyle RW

更新日期：2006-09-01 00:00:00

abstract：:Photodynamic therapy is a very important technique for the eradication of widespread oesophageal mucosal disease which has the potential to degenerate to cancer. Patients unsuitable or unwilling to undergo radical therapy can be cured using photodynamic therapy. We predominantly treat patients with high-grade dysplasi...

journal_title：Photodiagnosis and photodynamic therapy

authors： Barr H,Kendall C,Bazant-Hegemark F,Stone N

更新日期：2006-06-01 00:00:00

abstract：:Photodynamic therapy (PDT) was started in the People's Republic of China in the early 1980s after domestically produced hematoporphyrin derivative (HpD) became available. Since then, numerous photosensitizers have been synthesized and evaluated. Several promising ones have undergone clinical investigations and a few h...

journal_title：Photodiagnosis and photodynamic therapy

authors： Huang Z

更新日期：2006-03-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a clinically approved therapeutic modality used for the management of several types of tumors as well as non-malignant diseases. Most of the effects of this treatment regimen result from direct action of singlet oxygen and reactive oxygen species. However, accumulating evidence indicates ...

journal_title：Photodiagnosis and photodynamic therapy

authors： Nowis D,Stokłosa T,Legat M,Issat T,Jakóbisiak M,Gołąb J

更新日期：2005-12-01 00:00:00

abstract：:We present a novel case of an elderly patient with a Barrett's adenocarcinoma in the presence of an Angelchik prosthesis. We aim to draw attention to issues relating to metaplastic Barretts' oesphagus and its adenocarcinoma complications and highlight relevant issues in multimodal endoscopic management and palliation ...

journal_title：Photodiagnosis and photodynamic therapy

authors： Jenkins JT,Charles A,Mitchell KG,Fullarton GM

更新日期：2005-09-01 00:00:00

abstract：:The success of PDT and its establishment into the existent hall of therapeutic modalities depends on the collection of reported experiences from around the world. In that sense, it is important to report approaches taken by different countries and what their views are on the future of PDT. Following this idea, we pres...

journal_title：Photodiagnosis and photodynamic therapy

authors： Bagnato VS,Kurachi C,Ferreira J,Marcassa LG,Sibata CH,Allison RR

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The potential application of TOOKAD(®)-PDT for the treatment of blood vessels was investigated. TOOKAD(®) (WST09), a novel palladium-bacteriopheophorbide absorbs light in the near IR with a high quantum yield of intersystem crossing. Our study assessed the efficacy of this drug in inducing vascular damage wi...

journal_title：Photodiagnosis and photodynamic therapy

authors： Rück A,Böhmler A,Steiner R

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The Yorkshire Laser Centre team have been engaged in photodynamic therapy (PDT) since 1990. In this article we review our experience in bronchoscopic PDT for lung cancer and outline our current indications and results. METHODS:160 patients in 2 groups entered into a prospective study: Group A (N=144) were s...

journal_title：Photodiagnosis and photodynamic therapy

authors： Moghissi K,Dixon K,Thorpe JA,Oxtoby C,Stringer MR

更新日期：2004-11-01 00:00:00

abstract：:We report the case of a patient with recurrence of follicular carcinoma of the thyroid 8 years after surgical resection followed by external beam radiotherapy and radio-iodine treatment. The patient was treated by endoscopic photodynamic therapy (PDT) with complete endoscopic response after 12 months with good symptom...

journal_title：Photodiagnosis and photodynamic therapy

authors： Barber P,Deiraniya AK,Allen E

更新日期：2004-05-01 00:00:00

abstract：:Archival biopsy materials from 20 randomly selected asymptomatic volunteers from the Czech uranium miners (CZ UM) risk group (n=98) were examined for p21 and ki-67 immunostatning. There were 16 areas with normal respiratory epithelium and 22 areas with bronchial intra-epithelial neoplasia (IEN). Normal and IEN areas w...

journal_title：Photodiagnosis and photodynamic therapy

authors： Horvath TA,Hirano T,Horvathova MD,Vomela J,Vyzula R,Cı́halová M,Dorociak F,Ebihara Y,Furukawa K,Habanec B,Ikeda N,Kakihana M,Klusáková J,Okada S,Rejthar A,Stratil D,Shaffi-Sahely A,Smajer B,Spelda S,Tsuboi M,Vagun

更新日期：2004-05-01 00:00:00